[Changes in the duodenal mucosa in Whipple's disease]. / Izmeneniia slizistoi obolochki dvenadtsatiperstnoi kishki pri bolezni Uipla.

A case of Whipple's disease is described in a male patient of 43 who has been previously examined in different hospitals for six years. The diagnosis was established after surgery and histological examination of the duodenum biopsy. Infiltration of the tunica propria of the duodenum with PAS-positive macrophages was observed. Therapy with rondomycin in combination with GUMET-P produced a response but the recurrence took place after therapy. A new operation was followed by peritonitis and pneumonia which terminated in the patient's death.

[A rare tumor of the knee joint]. / Redkaia opukhol' kolennogo systava.

The tumour in a male of 62 consisted of vesicular vacuolized cells in a myxomatous substance. References are given as to the morphological similarity between chondrosarcoma and so-called chordoid-sarcoma. At the light and electron microscopic level the signs of incomplete chondrogenesis are found, this permitting one to consider the tumour as a myxoid variant of chondrosarcoma.

[Morphologic changes of the small intestine and lymph nodes in alpha-chain disease]. / Morfologicheskie izmeneniia tonkoi kishki i limfaticheskikh uzlov pri bolezni al'fa-tsepei.

Literature and original data are reported on a case of alpha-chain disease associated with small intestine lymphoma in a male patient aged 20. The disease manifested clinically with chronic diarrhea, malabsorption, hypoproteinemia, hypocalcemia, cachexia, discretely detected alpha-chain monomer. Morphologically, there was lymphoplasmacyte infiltration of the intestinal mucosal layer; capsule collagenization, clustering immunoblasts among microlymphocytes, a pronounced macrophagal reaction, intercellular crystalloid and lymph masses, follicular pattern disappearance, sites of cellular polymorphism revealed in an axillary lymph node. The latter finding evidenced for developing immunoblastic sarcoma.

[Local tumor-like amyloidosis of the larynx]. / Lokal'nyi opukholevidnyi amiloidoz gortani.

The authors describe a rare case of local tumour-like laryngeal amyloidosis in a patient, 61, with clinically observed increasing hoarseness during a 10-month period. The amyloid absorbed Congo red, and its ultrastructure was typical. The role of fibroblasts is confirmed in the formation of the fibrillar component of amyloid protein. Phenomena of amyloidoclasy are described.